Margaret K Yu Selected Research

apalutamide

7/2021	Association of Molecular Subtypes With Differential Outcome to Apalutamide Treatment in Nonmetastatic Castration-Resistant Prostate Cancer.
1/2020	Pharmacokinetics, Safety, and Antitumor Effect of Apalutamide with Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer: Phase Ib Study.
1/2020	Efficacy and Safety Exposure-Response Relationships of Apalutamide in Patients with Nonmetastatic Castration-Resistant Prostate Cancer.
1/2019	Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer.
10/2018	Effect of apalutamide on health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: an analysis of the SPARTAN randomised, placebo-controlled, phase 3 trial.
4/2018	Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer.
1/2018	Apalutamide and Metastasis-free Survival in Prostate Cancer.
1/2018	An open-label, multicenter, phase Ib study investigating the effect of apalutamide on ventricular repolarization in men with castration-resistant prostate cancer.
7/2017	Safety and Antitumor Activity of Apalutamide (ARN-509) in Metastatic Castration-Resistant Prostate Cancer with and without Prior Abiraterone Acetate and Prednisone.
12/2016	Phase 2 Study of the Safety and Antitumor Activity of Apalutamide (ARN-509), a Potent Androgen Receptor Antagonist, in the High-risk Nonmetastatic Castration-resistant Prostate Cancer Cohort.

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Margaret K Yu Research Topics

Disease

22	Prostatic Neoplasms (Prostate Cancer) 07/2021 - 08/2014
6	Neoplasms (Cancer) 07/2021 - 10/2004
6	Neoplasm Metastasis (Metastasis) 07/2021 - 10/2004
4	Hypertension (High Blood Pressure) 02/2015 - 01/2012
3	Exanthema (Rash) 01/2020 - 04/2018
2	Chronic Renal Insufficiency 01/2022 - 07/2015
2	Disease Progression 01/2020 - 11/2014
1	Weight Loss (Weight Reduction) 01/2020
1	Arthralgia (Joint Pain) 01/2020
1	Fatigue 01/2020
1	Liver Diseases (Liver Disease) 01/2019
1	Renal Insufficiency (Renal Failure) 01/2019
1	Azotemia 01/2019
1	Acute Kidney Injury (Acute Renal Failure) 01/2019
1	Hypothyroidism 04/2018
1	Kidney Diseases (Kidney Disease) 01/2018
1	Heart Diseases (Heart Disease) 02/2015
1	Muscular Diseases (Myopathy) 12/2014
1	Hyperglycemia 12/2014
1	Pain (Aches) 11/2014
1	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 08/2014
1	Hypokalemia 08/2014
1	Glucose Intolerance 08/2014
1	Obesity 08/2014
1	Chronic Kidney Failure (Chronic Renal Failure) 05/2014
1	Dyslipidemias (Dyslipidemia) 01/2013
1	Carcinogenesis 07/2004
1	Inflammation (Inflammations) 07/2004

Drug/Important Bio-Agent (IBA)

13	Abiraterone AcetateIBA 01/2020 - 08/2014
10	apalutamideIBA 07/2021 - 12/2016
8	Prednisone (Sone)FDA LinkGeneric 11/2020 - 11/2014
8	AndrogensIBA 01/2019 - 08/2014
7	abirateroneIBA 01/2017 - 08/2014
4	Prostate-Specific Antigen (Semenogelase)IBA 10/2018 - 07/2015
2	Biomarkers (Surrogate Marker)IBA 07/2021 - 07/2015
2	antiarrhythmic peptide (AAP)IBA 11/2020 - 07/2017
2	Androgen Receptors (Androgen Receptor)IBA 01/2020 - 04/2018
2	AlbuminsIBA 01/2019 - 07/2015
2	Prednisolone (Predate)FDA LinkGeneric 12/2014 - 12/2014
2	GlucocorticoidsIBA 12/2014 - 08/2014
2	Docetaxel (Taxotere)FDA Link 12/2014 - 12/2014
2	ProdrugsIBA 12/2014 - 08/2014
2	Hemoglobins (Hemoglobin)IBA 05/2014 - 01/2013
1	Phenobarbital (Luminal)FDA Link 07/2021
1	Starch (Cornstarch)IBA 01/2019
1	Colloids (Colloid)IBA 01/2019
1	Dietary ProteinsIBA 01/2019
1	ElectrolytesIBA 01/2019
1	enzalutamideIBA 01/2017
1	Androgen Receptor AntagonistsIBA 12/2016
1	CreatinineIBA 07/2015
1	Alanine Transaminase (SGPT)IBA 02/2015
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2014
1	Hydrocortisone (Cortisol)FDA LinkGeneric 08/2014
1	Acetates (Acetic Acid Esters)FDA Link 08/2014
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2013
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2013
1	Diphosphonates (Bisphosphonates)IBA 10/2004
1	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 07/2004
1	Proteins (Proteins, Gene)FDA Link 07/2004
1	Thioredoxin-Disulfide ReductaseIBA 07/2004

Therapy/Procedure

20	Castration 07/2021 - 11/2014
6	Therapeutics 01/2019 - 10/2004
6	Drug Therapy (Chemotherapy) 01/2017 - 11/2014
2	Aftercare (After-Treatment) 07/2017 - 01/2017
1	Cardiopulmonary Resuscitation (CPR) 01/2022
1	Length of Stay 01/2019
1	Terminal Care (Care, Terminal) 01/2018
1	Duration of Therapy 01/2016
1	Oral Administration 07/2015
1	Life Support Care 11/2014
1	Glycemic Control 01/2012